The night manager is Jonathan, a veteran of clandestine operations. In flight from a failed marriage and his own past, he has taken refuge in the luxury hotel trade. Yet he finds no escape from his demons. Driven by a desire for atonement and by an inherited patriotism, Jonathan allows himself to be recruited as a British secret agent with a mission to expose the murderer of the woman he himself betrayed. His odyssey takes him across Britain and Canada to the Caribbean and the jungles of Panama. But there are more treacherous jungles still in Whitehall and Washington.